It is a waste of time. For example, in the Phogoth strike on the Moon, the area after your ghost decodes 3 runes, you come to a room where there is the Ogre and the Knight, you kill those, and after that you can literally just run past all those monsters and go straight to Phogoth.
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You can actually just jump over the ogre as well, no damage taken.
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True, he's just so easy to oil I usually just do it as I walk towards him :P