Have you properly uninstalled the Nvidia Drivers and THEN installed the AMD Drivers using DDU (Display Driver Uninstaller) ? Also check if Resizable BAR / SmartAccess Memory is enabled in the BIOS/UEFI.
Lastly, I have made the experience that Depth of Field just destroys performance, disabling it solved that for me.
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yes, I have done the DDU in safe mode and reinstalled drivers, have Resizable BAR / SAM enabled. I will look into depth of field.