If the Witness him/herself is paracausel, how can we defeat them? And would we want to?
My take on it is that we won't fight the Witness head on but we will stave off their attacks in some way. I'm looking forward to seeing how this all unfolds in Lightfall and the Final Shape.
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With everything we've seen So far no. We might be able to trap it for a time, like how the Traveler was caged.