1) Significant performance drops and stuttering in various areas. Can always be reproduced in the Tangled Shore at Thieves' Landing. FPS holds steady in the 40's. During these extreme performance issues, GPU and CPU utilization are both relatively low. This occurs regardless of which power profile is being used for the system; I normally play with the "AMD Ryzen High Performance" power profile. My PC is a Ryzen 9 3950X, Radeon RX 6900 XT, 64GB RAM, with a PCIe Gen 4 NVMe on a fresh Windows 10 installation. Prior GPU on the same system was a GTX 1080, and it had no performance issues in D2. After replacing the GTX 1080 with the RX 6900 XT the performance in D2 dropped significantly. As a last resort in troubleshooting this issue, I formatted all drives and reinstalled Windows 10 prior to reinstalling the game only to see no difference in D2 performance. 2) All other apps and non-necessary background processes are shut down when the issue occurs. Applicable points from the "suggestions" list have been tried with no change in performance. 3) DxDiag: [url]https://pastebin.com/smiALVRK[/url] I'd like to note that the drop in performance seems to be similar to a drop in performance seen in CryEngine 3 games when running on AMD GPUs - this drop in performance in CE3 games seems to be related to low GPU utilization during drawcalls having higher zpass and shadows operations. This is purely speculation, but perhaps an issue in AMD's driver is causing the performance issues in both D2 and CE3, and something about higher drawcall operations and some sort of bottleneck occuring during those operations might be a commonality between both CryEngine 3 and Destiny 2's engines. Perhaps Bungie could leverage AMD in some way to help sort this is out, AMD might make a driver adjustment, and more than one game will get fixed. ;)