First I went with the brotherhood because they're bamf's. Then the railroad cos I sort of relate to it more. Minutemen is good if you want to keep the former 2 alive as well.
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My only problem with the BoS is that their extremely racist and a bit hypocritical, but you gotta respect their loyalty to their cause and their impressive military strength. The Railroad is like modern SJWs: if you don’t agree with them, you’re evil. But I can get down with helping out fellow sentient beings. The Institute’s motives are actually commendable, with them wanting to return humanity to its former glory, but their practices are brutal and inhumane and they lack a true sense of humility.