RNG is RNG. Even with modifiers, you can get extreme runs of no drops. It happens all the time. In one instance it happened to me in GW2 I went for 3 weeks not getting "loot" other than basic items for materials. I did everything I could do increase my drop rates, but still got jack. I was mighty peeved, but the next time I played around 2 months later I had one of the best runs of RNG I have had in a game and ended up with some top level gear on multiple characters. At one point a few players like me were getting drops like crazy during an event that made some people go nuts and accuse people of hacking. RNG really is a fickle beast.