This is probably the best strategy for Prison of Elders... Step 1) Find a nice spot with decent cover (some may call this a cheese spot) (Keep in mind that if there is any point in which a major or ultra invades your personal space, use your heavy!) (Also, if you are being overwhelmed, RUN like hell from the area! The enemies will follow you. Once you return to your main spot you should have less on your plate than before) Step 2) Focus fire on Tier 1 enemies. (Congratulations, there are less things to shoot you!) Step 3) Focus fire on Tier 2 enemies. (Congratulations, you have some alone time with Mr. Bulletsponge) Step 4) Now, shoot the boss! Step 5) The boss should reach a specific amount of health (around 75%, 50%, and 25%) until his friends start showing up again. Step 6) Once his annoying friends show up, repeat Step 2.. (DO NOT GET GREEDY IT WILL BE YOUR END!) If this has helped you, I am glad. If you have an alternative strategy, cheese or found this completely bleep-ing useless, please leave a comment.