Mass effect had a (better) story and I really loved me3mp. But after playing the story through multiple times and logging over 1100h in me3mp I feel it's a bit seen game. So now it's Destiny over Mass Effect for me. Hope this changes when ME4 (or whatever it will be called) comes out :)
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Im hoping ME4 uses the strike/mission layout from destiny for PVE instead of the wave combat.