"The Wolves are near, she is a fool if she thinks she can control them"
I hang around The Speaker often cause' he tends to spill some good stuff relating to the story and I heard that little tidbit, so I think that can give us a pretty good idea of what the House of Wolves is going to be about.
You can hear some pretty interesting stuff if you loiter around long enough, I admire the amount of dialogue Bungie have put in.
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The House of Wolves gets tired of her and tries to find a new Kell. We already know what it is. A lame excuse to shoot some more Fallen.