It's in the title! What's your favorite? What makes it your favorite? Gameplay, story, Multiplayer?
I love the Dishonored and Bioshock series. I think they were total package games. They were fun, great stories, just the right length, great DLC.
I'd love to hear yours!
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It's between Diablo and Borderlands for me. Tough choice, both are great in their own ways.