At least the lives of gen 3 synths. They have a free will, consciousness and emotions just like humans.
But on the other hand. They can be a serious threat to humanity. They are artificial. They are not created by nature. They have no soul. Or have they?
I always find myself on the fence.
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If they treat Mister Handies and Eyebots like they have purposes, then Synths should deserve some too. Nick Valentine, for example, when he was being held by Triggermen, they treated him like a dirty animal.