https://www.youtube.com/watch?v=c7rJLQlZTY4
The old guides on this dont work anymore because chests take forever to respawn in an area. Going into another area usually doesnt fix it. If you open 5 or 6 chests within 3 minutes they stop spawning for a 5 to 10 minute period. Using this method you can get around that and get your hadium flakes done very quickly.
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I found that combining the Flake grind with the Ultra Knight grind was the best way to keep it feeling worthwhile. 5-7 Flake Chests and 1 UltraKnight then orbit and back again. The knight drops plenty of 200glimmer items when he doesn't produce an exotic I was buying synths just to keep the glimmer down. (that was before weapon parts.. now i'd be buying them)