Ok so I I need 45 fragments to get the quest from Eris to get the malice, I have 42. The last 3 I need come from court of oryx. Do I have to wait a week for refresh to get my fragment or can I just keep going back until I get them?
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You can go in whenever you like to get them! :)
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If they are the tier 2 ones, you can get them anytime. The tier 3 fragments are boss specific and you will need to wait until the appropriate boss is here for the week.