I love deadpool too bro, funniest character ever. But let's be real here, if he faced thanos wielding the infinity gauntlet he'd lose
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Or galactus. But let's not get over our heads.
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Exactly, and I'm sure characters like them from other universes could take him out [spoiler]but he'd just kill them with his puns[/spoiler]
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And his regenerative feature would always bring him back. He's immortal.