Prove me wrong. I'm a lore expert on Destiny, so odds are I can refute any argument you provide that favors Destiny. Vegeta and Goku would beat the entire Destiny universe in a fight.
Lets also assume they know the mechanics for the VoG and Crota's End.
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It's kind of pointless comparing the strengths of fictional characters from two different universes. I could write a story with characters that are utterly invincible and have the power to erase anything from existence just by thinking about it for a second. They would be more powerful than DBZ characters, but that doesn't really mean anything.