Pretty much most of the Assassins Creeds. Specifically when:
[spoiler]Lucy[/spoiler] dies
[spoiler]Captain Kidd[/spoiler] dies :,(
[spoiler]Elise[/spoiler] dies
[spoiler]EVERYONE -blam!-ING[/spoiler] dies
Also the cutscene with Ezio securing the pieces of Eden when he is all old and stuff. Just seems sad.
English
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Desmond... :(
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...people actually cared for Desmond ?...
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Yeah, I know people who did. Plus the games kinda went downhill after he died, in terms of storyline. So thats pretty sad. Lol