Not necessarily the ending of the whole game, but the ending of several missions in Mass Effect 3. *cough* Tuchanka *cough*
"Would've liked to run tests on seashells....."
I cried.
That, and the end of the Overlord DLC mission in Mass Effect 2.
"It all seemed harmless..."
English
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Run the Tuchanka mission with a renegade play through. I haven't played the game since.
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The very first time I played that mission, I did the Renegade option. Why.
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A video game has never made me feel that dirty.
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I felt like a despicable person after doing that. I was trying to get both the Krogan and Salarians in my alliance. Instead, I was forced to watch one of the most heart-wrenching scenes to ever exist in a video game.
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https://m.youtube.com/watch?v=dBNVcMmg9Fs
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Edited by Recon SR2: 2/18/2015 11:47:26 AMYep, definitely heart-wrenching. That is still one of the saddest things that I have ever seen in a video game. That cutscene is why I will never be able to do a full Renegade Playthrough.